Plasma cholinesterase deficiency in a neonate.
نویسندگان
چکیده
We report a two-day-old infant who had a period of apnoea lasting six hours following the intravenous administration of succinylcholine (Sch). The results of her plasma cholinesterase level and dibucaine number indicate a congenital absence of plasma cholinesterase (PChE) enzyme, although both parents and siblings had normal cholinesterase levels and dibucaine numbers. This is believed to be the youngest reported case of prolonged apnoea after the administration of succinylcholine.
منابع مشابه
RELATIONSHIP BETWEEN SUCCINYLCHOLINEINDUCED APNEA AND DIBUCAINE NUMBER IN PATIENTS WITH GENETIC DEFICIENCY OF PLASMA CHOLINESTERASE
In this study, a commercially available kit in which propionylthiocholine is used as a substrate and a dibucaine solution to determine the variants of the enzyme were utilized. Plasma cholinesterase activity of 151 patients who underwent different operations was measured during a period of six months. The mean±SD of the enzyme activity in 150 patients was 4.39±1.17 kU/L .. Seventeen patie...
متن کاملDelayed recovery from paralysis associated with plasma cholinesterase deficiency
INTRODUCTION This case was to describe a patient presented a 6 h length of apnea associated with low cholinesterase activity. CASE DESCRIPTION A 32 years old female patient (body weight 50 kg, height 160 cm) was admitted to the hospital for laparoscopy combined with hysteroscopy exploration. The preoperative interrogation revealed no significant personal or family history of adverse reaction ...
متن کاملPlasma prolactin concentrations during high-dose opioid anaesthesia.
train-of-four on a peripheral nerve stimulator and sustained head lifting. General anaesthesia for ECT has three main functions: lack of awareness of the therapy; modification of the motor effects of the fit to prevent injury; fast recovery of reflexes and consciousness enabling early airway protection. Suxamethonium is the best neuromuscular blocking drug for ECT, because of its short duration...
متن کاملIntersting SAR studies of pregnane alkaloids isolated from genus Sarcococca against cholinesterase enzymes
The genus Sarcococca is widely distributed in South-East Asia and it comprises 14 species. The genus is traditionally used for gastrointestinal ulcers, infections, pain and in rheumatic fevers. Recently, our group has derived a comprehensive SAR relationship picture for a new series of natural cholinesterase inhibitors isolated from Sarcococca saligna (syn. S. pruniformis, Buxaceae). The fracti...
متن کاملROLE OF IRON DEFICIENCY ANEMIA IN CHILDBEARING WOMEN ON NEONATAL WEIGHT
Iron deficiency is one of the most common nutritional problems in the world, It is frequently found in both developed and developing countries and mainly affects women of childbearing age. The aim of this study was to investigate the relationship of iron deficiency anemia in pregnant women on neonatal weight. The study subjects were a group of 241 women aged between 20 and 34 years who wer...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Canadian journal of anaesthesia = Journal canadien d'anesthesie
دوره 40 6 شماره
صفحات -
تاریخ انتشار 1993